KUHS First Professional MBBS Degree Examination 106001 August 2015 BIOCHEMISTRY PAPER II Question Paper

106001 August 2015 BIOCHEMISTRY PAPER II

Q.P.Code 106001 Reg. No.:???????
First Professional MBBS Degree Examinations – August 2015
BIOCHEMISTRY – PAPER II
Time : 3 hrs Max marks : 50

? Answer all questions
? Draw diagrams wherever necessary
Essay (10)1. Describe the process of transcription. What are the post transcriptional
modifications. Mention two inhibitors of transcription. (6+3+1=10)Short essays (2×5=10)2. Describe uric acid formation and mention the clinical significance of its
estimation.
3. Mention the normal level of serum calcium. Explain the hormonal regulation of
serum calcium
Short notes (5×3=15)4. Acute intermittent porphyrias.
5. Mention the normal sodium level and clinical manifestation of hyponatremia.
6. Applications of radio activity.
7. Metabolic acidosis.
8. Creatinine clearance test.
Answer briefly (5×2=10)9. List two reactions where the folic acid is the co-enzyme.
10. Principles of colorimetry.
11. How benzoic acid and sulfanilamide are detoxified in human body.
12. Explain why edema develops in hypo albuminemia.
13. List the different classes of immunoglobulins and mention the functional role of
any one.
Give precise answers (5×1=5)14. List anti vitamins and mention one example.
15. Co-enzyme functions of biotin.
16. Name two biochemical markers of cancer.
17. Reverse transcriptases.
18. Proto-oncogenes.
***************