KUHS First Professional MBBS Degree Examination 105001 August 2015 BIOCHEMISTRYPAPER I Question Paper

105001 August 2015 BIOCHEMISTRYPAPER I

Q.P. Code: 105001 Reg. no.: ???????
First Professional MBBS Degree Examinations – August 2015
BIOCHEMISTRY- PAPER I
Time: 3 Hours Total Marks: 50
? Answer all questions
? Draw diagrams wherever necessary
Essay (10)1. Enumerate the components of electron transport chain. Describe the synthesis of
ATP. Indicate the site specific inhibitors. Mention two examples for uncouplers.
(4+2+2+2=10)Short essays (2×5=10)2. Gluconeogenesis
3. Diagnostic significance of serum enzymes
Short notes (5×3=15)4. Digestion of carbohydrates
5. Essential fatty acids
6. Denaturation
7. Principle of chromatography
8. Name three glycogen storage diseases and its biochemical defect
Answer briefly (5×2=10)9. Role of carnitine
10. Define isoelectric pH. State properties of a protein at its isoelectric pH
11. Importance of HMP shunt pathway
12. Sources of ammonia
13. Allosteric enzymes
Give precise answers: (5×1=5)14. Name the biochemical defect in Nieman-pick disease
15. Zymogen activation
16. Mention the reaction catalyzed by ATP-citrate lyase
17. Mention two biologically active peptides
18. Mention one therapeutic use of enzyme
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