KUHS Second Professional MBBS Degree Examination 202001 September 2014 Pharmacology- Paper II Question Paper

202001 September 2014 Pharmacology- Paper II

Q.P. Code: 202001 Reg. no.: ???????
Second Professional MBBS Degree Supplementary Examinations,
September 2014
Pharmacology- Paper II
Time: 2 Hours Total Marks: 40
? Answer all questions
? Draw diagrams wherever necessary
Essays: (2×6=12)1. Classification of fluoroquinolones .Describe the mechanism of action, therapeutic uses and
adverse effects of sparfloxacin. (2 + 2+ 2 =6)
2. Read the case history and answer the following questions. Mr. Raman 32 years has
developed severe epigastric pain after taking tab. Ibuprofen 400mg tds for his joint pain
? Mention two drugs used in NSAID induced gastric ulceration
? Mechanism of action of proton pump inhibitors
? Drugs for eradication of H.pylori infection
Short notes: (5×3=15)3. Bisphosphonates
4. Adverse effects of aminoglycosides
5. Anti thyroid drugs
6. Rifampicin.
7. Taxanes in cancer chemotherapy.
Answer briefly: (5×1=5)8. Two uses and two adverse effects of oral contraceptive pills
9. Mechanism of action of metoclopramide
10. Two advantages of human insulin
11. Specify the important spectrum of vancomycin
12. Rationale of estrogen in hormone replacement therapy
Name two drugs: (8×1=8)13. Chloroquine resistant malaria.
14. Urinary tract infections
15. Immunosuppressive in organ transplantation
16. Irritable bowel syndrome.
17. Gram negative septicemia
18. Tocolytics
19. Aromatase inhibitors
20. Retro viral infections
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