KUHS Second Professional MBBS Degree Examination 201001 September 2015 Pharmacology- Paper I Question Paper

201001 September 2015 Pharmacology- Paper I

Q.P. Code: 201001 Reg. no.: ???????
Second Professional MBBS Degree Supplementary Examinations,
September 2015
Pharmacology- Paper I
Time: 2 Hours Total Marks: 40
? Answer all questions
? Draw diagrams wherever necessary
Essays: (2×6=12)1. Enumerate four groups of drugs used in the treatment of Parkinson?s disease. Describe the
pharmacological actions and adverse effects of levodopa. What is the advantage of combining
levodopa with the peripheral decarboxylase inhibitor. (2+3+1= 6)2. Read the clinical problem and answer the following questions: 30 years old man was admitted
in emergency ward with acute abdominal pain. After diagnosed with acute appendicitis, he was
taken for surgery. On the operation table, after administration of a skeletal muscle relaxant,
patient developed difficulty in breathing and went in for apnoea.
? Which skeletal muscle relaxant is responsible for this reaction.
? What is the reason for the apnoea.
? How will you manage the patient. (1+3+2=6)Short notes: (5×3=15)3. Trans dermal therapeutic system
4. Amphetamine
5. Second generation antihistamines
6. Tramadol
7. Ramipril
Answer briefly: (5×1=5)8. Rationale for use of calcium channel blockers in angina
9. Rationale for use of ethanol in methanol poisoning
10. Rationale for use of prostaglandin in acid peptic disease
11. Rationale for use of physostigmine in atropine poisoning
12. Pharmacovigilance
Name two drugs: (8×1=8)13. Cholinesterase reactivators
14. Intravenous general anesthetics
15. Inhalational steroids
16. Centrally acting muscle relaxants
17. Nasal decongestants
18. Pure opioid antagonists
19. Low molecular weight heparins
20. Cardio selective beta blockers
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