106001 February 2014 BIOCHEMISTRY PAPER II
Q.P.Code 106001 Reg. No.:???????
First Professional MBBS Degree Supplementary Examinations, February 2014
BIOCHEMISTRY – PAPER II
Time : 3 hrs Max marks : 50
? Answer all questions
? Draw diagrams wherever necessary
Essay (10)1. Describe the source, dietary requirements, biochemical functions and deficiency
manifestations of vitamin A. (1+1+4+4=10)Short essays (2×5=10)2. Explain briefly on blood buffers and add a note renal mechanism of maintaining acid
base balance. (2+3=5)3. Describe the process of DNA replication. (5)Short notes (5×3=15)4. Abnormal hemoglobins
5. Tumor markers
6. Liver function tests
7. Immunoglobulins
8. Gene therapy
Answer briefly (5×2=10)9. Folate antagonists
10. Normal serum concentration of sodium and potassium
11. ELISA ( Enzyme linked immunosorbent assay )12. What is the normal serum calcium level. Name the hormones regulating serum calcium
13. Enzyme defect in lesch-nyhan syndrome and orotic aciduria
Give precise answers (5×1=5)14. Deficiency of vitamin C
15. Examples for point mutation
16. What are BJP(Bence jones proteins)17. Name two oncogenes
18. Normal serum uric acid level
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