KUHS First Professional MBBS Degree Examination 106001 August 2013 BIOCHEMISTRY PAPER II Question Paper

106001 August 2013 BIOCHEMISTRY PAPER II

Q.P.Code 106001 Reg. No.:???????
First Professional MBBS Degree Examinations, August 2013
BIOCHEMISTRY – PAPER II
Time : 3 hrs Max marks : 50
? Answer all questions
? Draw diagrams wherever necessary
Essay (10)1. Discuss in detail the mechanism by which kidney maintains the blood pH. What is meant
by metabolic acidosis and how it is compensated. (1+6+3=10)
Short essays (2×5=10)2. Explain the degradation of haem
3. Discuss the process of transcription in prokaryotes
Short notes (5×3=15)4. Cytochrome p450
5. List the different functions of plasma proteins.
6. Describe the Wald?s visual cycle.
7. Antioxidants
8. Discuss the base repair mechanism of DNA
Answer briefly (5×2=10)9. Pellagra
10. Factors affecting iron absorption
11. DNA finger printing
12. Define gout and name three drugs used to treat gout.
13. Orotic aciduria
Give precise answers (5×1=5)14. Mention two features of mitochondrial DNA
15. List the functions of restriction endonucleases.
16. Define tumor markers and mention one example
17. The normal albumin-globulin ratio and mention a condition in which it is reversed
18. Mention the examples of partially acceptable missense mutation and unacceptable
missense mutation
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