KUHS First Professional MBBS Degree Examination 105001 August 2012 BIOCHEMISTRYPAPER I Question Paper

105001 August 2012 BIOCHEMISTRYPAPER I

Code: 105001 Reg. no.: ???????
First Professional MBBS Degree Examinations, August 2012
BIOCHEMISTRY- PAPER I
Time: 3 Hours Total Marks: 50
? Answer all questions
? Draw diagrams wherever necessary
Essay (10)
1. Mention the reactions by which glycine is synthesized and catabolized. Add a note
on the specialized products formed and mention the disorders associated with glycine
metabolism. (2+6+2=10)Short essays (2×5=10)
2. Fatty acid synthase complex.
3. Describe the reactions of urea cycle. Discuss the interrelationship between urea
cycle and citric acid cycle.
Short notes (5×3=15)
4. Mention three examples of transmethylation reactions.
5. Ketosis
6. Secondary structure of proteins.
7. Importance of glutamine.
8. Covalent modification.
Answer briefly (5×2=10)
9. Hartnup?s disease.
10. Classification of glycolipids.
11. Uncouplers of oxidative phosphorylation.
12. Functions of cholesterol.
13. Significance of HMP shunt
Give precise answers (5×1=5)
14. Enzyme defect in maple syrup urine disease.
15. Epimer of glucose.
16. Normal level of serum albumin.
17. Name the biochemical test for phenylketonuria.
18. Important product of Rapaport- Leubering cycle in RBC

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