MGR University B-Pharmacy Fourth Year 564269 PAPER III – PHARMACOLOGY – II August 2018 Question Paper

564269 PAPER III – PHARMACOLOGY – II

THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY
(LN 4269) AUGUST 2018 Sub. Code: 4269
B.PHARM. DEGREE EXAMINATION
FOURTH YEAR
PAPER III – PHARMACOLOGY – II
Q.P. Code: 564269
Time: Three hours Maximum: 100 Marks

I. Elaborate on: (2 x 20 = 40)1. a) Classify Sulfonamides. Discuss the mode of action, Adverse Drug Reaction
and uses of Sulfonamides.
b) Discuss the development of drug resistance by microorganism against
anti-microbial agents.
2. a) Write elaborately on the general principals in the treatment of poisoning.
b) Write notes on Heavy Metal Poisoning.
II. Write notes on: (8 x 5 = 40)1. List out various Oral Contraceptives. Add a note on combined pill.
2. Classify Antiviral Agents. Discuss the mechanism of Nucloside Reverse
Transcriptase Inhibitors.
3. What are Plasma Volume Expanders? Give example. Write notes on Dextron.
4. Classify antihistamines. Discuss the pharmacological actions and uses H
1
receptor
antagonist.
5. Classify Anti-cancer agents. Write the mechanism of Alkylating Agents.
6. Define Conjunctivitis. Discuss the drugs used for the treatment of Conjunctivitis.
7. With suitable examples discuss the importance of Chronopharmacology.
8. Discuss the applications of Bio-Statistics in Pharmacy.
III. Short answers on: (10 x 2 = 20)1. Examples for Beta lactamase inhibitor.
2. Write the uses of Metoclopramide.
3. Name two Anabolic Steroids.
4. Give example for Parenteral Iron Supplements.
5. Write the Pathophysiological role of Pentagastrin.
6. Define Oxytocics and Tocolytics with example.
7. Mention the uses of Terbinafine.
8. What is British Antilewisite? Write its therapeutic application.
9. Define the term Immunomodulators with example.
10. List out the toxicities of Aminoglycosides.

********