MGR University B-Pharmacy Second Year 564256 PAPER I – PHYSICAL PHARMACEUTICS August 2018 Question Paper

564256 PAPER I – PHYSICAL PHARMACEUTICS

THE TAMIL NADU DR. M.G.R. MEDICAL UNIVERSITY (LN 4256) AUGUST 2018 Sub. Code: 4256
B.PHARM. DEGREE EXAMINATION
SECOND YEAR
PAPER I – PHYSICAL PHARMACEUTICS
Q.P. Code: 564256
Time: Three hours Maximum: 100 Marks
I. Elaborate on: (2 x 20 = 40)1. Define micromeritics. Explain the various methods to determine particle size
analysis.
2. a) Explain objectives, procedures and limitations of accelerated stability testing.
b) Explain briefly difference between flocculation and deflocculation suspension.
II. Write notes on: (8 x 5 = 40)1. Spreading coefficient.
2. Diffusion principles in biological systems.
3. Theory of emulsification.
4. Inclusion Complex.
5. Electrical properties of interface.
6. Purification of colloids.
7. Methods to adjust isotonicity.
8. Non-Newtonian system.
III. Short answers on: (10 x 2 = 20)1. Angle of repose.
2. BET equation.
3. Plug flow.
4. Surface tension.
5. Partition coefficient.
6. Schulze Hardy rule.
7. Multiple emulsion.
8. Micellar solubilization.
9. Chelates.
10. Yeild value.
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